| 英文名称 | Anti-CCL21/6Ckine（Chemokine （C-C motif） ligand 21） | | 中文名称 | 淋巴细胞趋化因子CCL21抗体 | | | | | 产品类别 | 兔抗人、大、小鼠CCL21抗体 | | 产品价格 | 0.2ml/890元 | | 产品标准 | 浓缩液（1mg/1ml） 亲和纯化抗体 | | 产品应用 | WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复） | | 产品介绍 |
CCL21 is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine （because it has six conserved cysteine residues instead of the four cysteines typical to chemokines）, exodus-2, and secondary lymphoid-tissue chemokine （SLC）.
CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7. In the cancer biology CCL21 seems to have multifaceted roles.
CCL21 attracts CCR7 bearing cells especially T and dendritic cells but also various cancer cells. Besides the antitumour role as leukocyte recruiting, CCL21 has been shown to facilitate dendritic cell functions and to exert an angiostatic effect.
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